sorry to bump an old post here, but I had to share my experience.
I had shingles, so a doctor prescribed me 5mg/500mg vicodin.. I wasn't too thrilled about that since I'm not a huge fan of pharmaceutical drugs... however the pain was really bad so I took half of one (i'm really short and i weigh 100 lbs). I didn't really feel anything for a while... so I took a hit of pot. Like 10 minutes later I was laying in bed and I was SO comfortable.... I can't explain it, it was the best feeling in the world. And then I got realllly tired and I fell asleep for a super long time and didn't remember a whole lot from the rest of the night. Everything seemed like a dream, it was crazy. It was the most calming feeling ever...

i took vicodin plain and i didn't feel anything... I guess it only works with pot haha