In my experience, even if you lay off for a couple days it really helps. Although, with tolerance breaks, the longer the better. I usually attempt at a week and get bloody blazed at the end. However, my tolerance comes back within days I feel like.
One of the best things I've found is smoking different strains. Different strains, different highs... better time
"We had two bags of grass, seventy-five pellets of mescaline, five sheets of high-powered blotter acid, a salt shaker half full of cocaine and a whole galaxy of multicolored uppers, downers, screamers, laughers....Also a quart of tequila, a quart of run, a case of Budweiser, a pint of raw ether, and two dozen amyls....But the only thing that worried me was the ether. There is nothing in the world more helpess and irresponsible than a man in the depths of an ether binge...."